RS 504393
- Product Name
- RS 504393
- CAS No.
- 300816-15-3
- Chemical Name
- RS 504393
- Synonyms
- RS 504393;RS-504393; RS504393;RS504393 >=98% (HPLC);6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spir...;CC chemokine receptor,RS504393,Inhibitor,RS 504393,inhibit,CCR,RS-504393;6-Methyl-1'-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidi;6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin];6-Methyl-1'-(2-(5-methyl-2-phenyloxazol-4-yl)ethyl)spiro-[benzo[d][1,3]oxazine-4,4'-piperidin]-2(;6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one;6-Methyl-1'-(2-(5-Methyl-2-phenyloxazol-4-yl)ethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one
- CBNumber
- CB5837883
- Molecular Formula
- C25H27N3O3
- Formula Weight
- 417.5
- MOL File
- 300816-15-3.mol
RS 504393 Property
- Density
- 1.28
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble1mg/mL, clear (warmed)
- form
- powder
- color
- white to beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0711
- Product name
- RS504393
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $152
- Updated
- 2024/03/01
- Product number
- SML0711
- Product name
- RS504393
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $633
- Updated
- 2024/03/01
- Product number
- 17330
- Product name
- RS 504393
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $45
- Updated
- 2024/03/01
- Product number
- 17330
- Product name
- RS 504393
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 17330
- Product name
- RS 504393
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $198
- Updated
- 2024/03/01
RS 504393 Chemical Properties,Usage,Production
Uses
RS 504393 is a small molecule antagonist at the CC chemokine receptor 2.
Uses
RS504393 has been used in mass spectrometry.
Definition
ChEBI: 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-2-spiro[1H-3,1-benzoxazine-4,4'-piperidine]one is a member of 1,3-oxazoles.
Biological Activity
Extremely selective CCR2 chemokine receptor antagonist (IC 50 values are 98 nM and > 100 μ M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC 50 = 330 nM) and ischemia-reperfusion injury in kidneys.
Biochem/physiol Actions
RS504393 is a highly selective CCR2 chemokine receptor antagonist. RS504393 inhibits MCP-1 chemotaxis and ischemia-reperfusion injury in kidneys.
storage
Store at +4°C
RS 504393 Preparation Products And Raw materials
Raw materials
Preparation Products
RS 504393 Suppliers
View Lastest Price from RS 504393 manufacturers
- Product
- RS 504393 300816-15-3
- Price
- US $5.50/KG
- Min. Order
- 1IU
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-10